why sickle cell anemia is very dangerous?

Sickle cell anemia is a hereditary disease that affects red blood cells. It’s one of the most common and usually most severe forms of a group of red blood cell disorders called sickle cell disease. In order to survive, your body needs these red blood cells to supply oxygen to its tissues. Red blood cells are produced in the bone marrow, the central part of the bones.

There, immature cells called blood stem cells can divide to make all types of blood cells, including red blood cells, and normal red blood cells are discharged.

They contain protein molecules called hemoglobin that carry oxygen around. Flexible red blood cells flow easily through your bloodstream and pick up oxygen in your lungs. In small air sacs in the lungs called alveoli, oxygen moves into the blood and binds to hemoglobin in red blood cells.

Then, the red blood cells deliver oxygen to cells throughout the body. In sickle cell anemia, there is a problem with your hemoglobin that makes your red blood cells sickle shape instead of round.

This is caused by a defective gene that is passed from both parents to children through genetic material in your cells called DNA.

DNA is made up of sections called genes. Two of the genes, called alpha-globin and beta-globin, contain the blueprints for making the hemoglobin proteins. In sickle cell anemia,

the beta-globin gene has changed or mutated. This mutation leads to the formation of an abnormal hemoglobin protein called hemoglobin S.

Hemoglobin S forms into rigid strands inside your red blood cells, which causes the red blood cell to be sickle-shaped. Sickle cells can block blood flow and can cause pain and tissue damage. And while normal red blood cells last 90 to 120 days, sickle cells only last ten to 20 days.

sickle cell anemia is very dangerous
Image by Narupon Promvichai from Pixabay

Your body may not be able to keep up with how fast the cells are destroyed. As a result, there are fewer red blood cells in your blood than normal. This condition is called anemia. The symptoms of sickle cell anemia vary by every people.

But may include episodes of pain in your body parts such as your hands and feet. Lower back. The chest and abdomen have a yellow tint in the whites of the eyes and skin called jaundice and feeling tired due to anemia over time.

Sickle cell anemia can lead to complications such as severe pain and damage to your eyes. Heart. Lungs. Liver. Kidneys and joints. Damage to your spleen, an organ that makes immune cells, can increase your risk of infections.

The risk for sickle cell anemia is highest among people with ancestors from SubSaharan Africa, Hispanic areas of South America, the Caribbean and Central America, Saudi Arabia, India, and Mediterranean countries. To find out more about sickle cell anemia, talk to your healthcare provider.

why sickle cell anemia is very dangerous?
Image by Michal Jarmoluk from Pixabay

By Amarjeet

Mr. Govind is the Author & Co-Founder of amarjeet.us. He has also completed his graduation in zoology on this blog, we keep sharing updates related to Helth every day.

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